Directory of Laboratory and Computing Research Resources
Brain Bank, Neuropathology
The Neuropathology Brain Bank at the University of Pittsburgh School of Medicine provides brain only autopsies for deceased pediatric or adult individuals who died with dementia, brain injury, or other neurological diseases. The brain bank has been established over 30 years ago and has accumulated >1000 neurodegenerative cases. Funds from the University of Pittsburgh Brain Institute have allowed us to broaden and expand our banking efforts. All cases receive a full diagnostic evaluation by a board-certified neuropathologist. Some portions of the brain tissue are banked and are made available to local, national and international investigators for qualified research studies. You may make a request by submitting a “Request for Tissue Specimen” at the website or by contacting us.
UPMC Hillman Cancer Center
For a complete listing of research resources available as part of the UPMC Hillman Cancer Center (formerly UPCI), please link to the Shared Resources web page.
- Animal Facility
- Biobehavioral Oncology Facility
- Biostatistics Facility
- Cancer Bioinformatics Services
- Cancer Genomics Facility
- Cancer Pharmacokinetics and Pharmacodynamics Facility
- Cancer Proteomics Facility (Luminex, Mass Spectrometry)
- Cell and Tissue Imaging Facility
- Chemical Biology Facility
- Cytometry Facility
- Hematopoietic Stem Cell Laboratory*
- Immunologic Monitoring and Cellular Products Laboratory
- In Vivo Imaging Facility
- Investigational Drug Services
- Tissue and Research Pathology
University Center for Social and Urban Research
The University Center for Social and Urban Research (UCSUR) was established in 1972 to serve as a resource for researchers and educators interested in the basic and applied social and behavioral sciences. As a hub for interdisciplinary research and collaboration, UCSUR promotes a research agenda focused on the social, economic, and health issues most relevant to our society.
UCSUR maintains a permanent research infrastructure available to faculty and the community with the capacity to:
- Conduct all types of survey research, including complex Web surveys
- Carry out regional econometric modeling
- Analyze qualitative data using state-of-the-art computer methods
- Obtain, format, and analyze spatial data
- Acquire, manage, and analyze large secondary and administrative data sets including Census data
- Design and carry out descriptive, evaluation, and intervention studies
- Provide information technology services for the collection, management, and analysis of sensitive research data to assure the highest levels of security and privacy.
Statistics Consulting Center
The Center for Statistics offers statistical consulting services, including design, data summarization, analysis, and interpretation of results. Researchers from various disciplines (within the arts and sciences, as well as clinical research and education) are welcome. Typically, only short-term consulting projects can be undertaken. The consulting is done by graduate students under the supervision of faculty members in the Department of Statistics.
Epidemiology Data Center
The Epidemiology Data Center (EDC) provides a research environment in which complex health questions can be explored and answered using the combined tools of biology and statistics. The EDC establishes collaborations with clinical researchers to design, conduct, and analyze multi-center randomized clinical trials and epidemiologic studies. To contribute to the development of new knowledge, the EDC develops and refines data collection, data management, computing, and statistical methods, with the ultimate goal of advancing treatment and prevention of disease.
The EDC has collaborated in over 100 research studies sponsored by the National Institutes of Health and other agencies. At any given time the EDC coordinates data management and analysis activities for 20 to 30 research projects sponsored by federal agencies as well as by industry. The current studies represent a variety of scientific designs including clinical trials, registries, and case control studies.
Center for Research on Health Care, Data Center
The CRHC Data Center mission is to support University of Pittsburgh faculty members in conducting high-quality clinical and translational research at the University of Pittsburgh. To meet this objective, the CRHC Data Center provides data management, statistical analysis, and graphics services to all University investigators.
The Food and Drug Administration (FDA) developed guidelines (Title 21 CFR Part 11) for electronic records to ensure the integrity and reliability of the electronic data; the CRHC Data Center creates databases that are compliant with these FDA guidelines.
The CBP/Pharmacology Machine Shop provides consultation, design and fabrication services to School of Medicine investigators who need specialized devices for experimental use and specialized clinical devices. The Shop personnel can diagnose and repair mechanical scientific machinery and equipment, and working in conjunction with the CBP/Pharmacology Electronics Shop, can also address the repair of electronically controlled scientific machinery and equipment. Services are fee based and an account is required at the time of request of service.
Clinical and Translational Science Institute(CTSI)
The mission of the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh is to improve the efficiency with which biomedical advances translate to improvements in the health of the community. CTSI is transforming the process of clinical and translational research through the provision of research and educational resources, thus training and enabling scientists to generate and translate new biomedical knowledge.
- Research Participant Registry
- Regulatory Core
- Clinical and Translational Research Center
- Design Biostatistics and Ethics Core
Luminex Core Laboratory
This facility uses the Laboratory Multianalyte Profiling (LabMAP™) system developed by Luminex Corporation. It is a flexible, easy-to-use protein analysis system that permits the simultaneous quantitative analysis of up to 100 different proteins, peptides, or DNA molecules in a single microtiter well. Multiplexing enables a comprehensive overview of complex biological systems and the inclusion of in-process controls using a minimum amount of sample. Potential applications include:
- functional genomics
- validation of drug leads
- secondary screening
- absorption and distribution
- high-throughput ELISA and Western blot assays.
The UPMC Hillman Cancer Center (UHCC) Luminex Core Laboratory can process and analyze samples using commercially available manufactured kits or unique Core developed kits. The UHCC Luminex Core Laboratory can also develop custom analyte Luminex assays using investigator-supplied antibodies and a protein standard. (formerly UPCI)
Rodent Behavior Analysis Core (RBAC)
See Preclinical Phenotyping Core (PPC)