NIH S10 Instrumentation Programs: Shared Instrumentation Grant (PAR-18-600 SIG) High-End Instrumentation (PAR-18-598HEI)


ORIP's S10 Instrumentation Grant Programs consist of two components: the Shared Instrumentation Grants (SIG) and High-End Instrumentation (HEI) Grants. These programs support purchases of state-of-the-art commercially available instruments to enhance research of NIH–funded investigators. Instruments that are awarded are typically too expensive to be obtained by an individual investigator with a research project grant. Every instrument awarded by an S10 grant is used on a shared basis, which makes the programs cost-efficient and beneficial to thousands of investigators in hundreds of institutions nationwide.

ORIP manages the S10 programs by issuing two Funding Opportunity Announcements (FOA) with one annual receipt date:

  • Shared Instrumentation Grant Program (SIG) (S10) funds grant awards in the $50,000 to $600,000 range
  • High-End Instrumentation Grant Program (HEI) (S10) funds grant awards in the $600,000 to $2,000,000 range


There is no limit on the number of applications an institution may submit, provided the applications request different types of equipment. However, if two or more applications are submitted for similar equipment, Dr. Rob Rutenbar, Senior Vice Chancellor for Research, must provide documentation stating that this is not an unintended duplication, but part of a campus-wide institutional plan. Because of this requirement, it is essential that the University of Pittsburgh coordinate its submissions. To allow enough time for this internal review, interested applicants must complete the internal application form accessible at Competition Space no later than Monday April 9, 2018. You will be asked to input the following information:

  • Instrument (name, manufacturer, model number, base cost);
  • Participating Investigators (listed by department, division, and/or institute);
  • a brief description of the research that will be supported by the requested instrument.

Applicants who do not respond to the internal process will not be permitted to submit an S10 application to the NIH. Questions regarding these funding opportunities or the internal competition process should be directed to Ryan Champagne: or 412.624.7410

Internal Due Date

Monday, April 9, 2018

Application Due Date

Thursday, May 31, 2018

Link to External Announcement