Research Resources - Laboratory and Computing
This directory provides links or contact information for laboratory, computing, and data analysis resources that are available to University investigators.
To submit updates, or to request the addition of a resource, please contact Paul Wood at firstname.lastname@example.org or (412) 648-9618.
For Pitt Biomedical Research Facilities' web site search.
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Biomedical Mass Spectrometry Center
The Biomedical Mass Spectrometry (BioMS) Center is a campus-wide shared facility dedicated to advancing the use and application of mass spectrometry in basic, translational, and clinical research. The center combines state-of-the-art high resolution mass spectrometry with classical biochemical approaches to identify and quantify biologically relevant proteins.
Not sure how to get started?
The BioMS center helps newcomers get started fast, by offering an in-gel protein identification service. Cut out your coomassie stained gel band and get it to us by noon on Monday and we will send you a list of identified proteins and post-translational modifications the following week.
Make us an extension of your lab.
Sometimes there is no substitute for doing it yourself. Faculty and students that want to gain first hand mass spectrometry experience are encouraged to work alongside the expert staff and other users in the center. We provide the bench space, instrumentation, and expertise. You provide the excitement and energy.
Want to discuss a specific project?
Nathan Yates (Center Director) and Xuemei Zeng (Asst. Director for Proteomics) regularly meet with investigators to discuss and plan collaborative research projects. To schedule a meeting, contact Dr. Nathan Yates.
Biomedical Research Imaging Resources Directory
This website provides searchable directory of the imaging resources and capabilities available to biomedical researchers at the University of Pittsburgh and Carnegie Mellon University.
- Biological Sciences Microscopy and Imaging Facility
- In Vivo Imaging Facility (IVIF) - Preclinical PET and PET-CT (UPCI)
- In Vivo Imaging Facility (IVIF) – Preclinical MRI (UPCI)
- In Vivo Imaging Facility (IVIF) – Preclinical Optical Imaging (UPCI)
- In Vivo Imaging Facility (IVIF) – Preclinical Ultrasound Imaging (UPCI)
- Center for Biological Imaging (CBI)
- Center for Ultrasound Molecular Imaging and Therapeutics
- Department of Neurobiology Microscopes
- Cryo-electron Microscopy (CryoEM) Facility
- Division of Laboratory Animals Research (DLAR) Imaging
- High Content Screening (HCS) Imaging Resources
- Hillman Live Cell Imaging Facility
- Laboratory of Physical Molecular Biology (chromatin fiber imaging)
- Magnetic Resonance Research Center (MRRC)
- Near Infrared Spectroscopy (NIRS) Brain Imaging Laboratory
- Neuroscience Imaging Center (NIC)/Neuroimaging Laboratory
- Ophthalmic Imaging Research Laboratory
- Pittsburgh NMR Center for Biomedical Research
- Positron Emission Tomography (PET) Facility
- Animal Imaging Core Facility (Rangos Research Center)
- Cell Imaging Core I and II Laboratories, (Rangos Research Center)
- Regional Biocontainment Laboratory (RBL) Clinical Imaging Core
- Nuclear Magnetic Resonance (NMR) Facility (Structural Biology)
Brain Bank, Neuropathology
The Neuropathology Brain Bank at the University of Pittsburgh School of Medicine provides brain only autopsies for deceased pediatric or adult individuals who died with dementia, brain injury, or other neurological diseases. The brain bank has been established over 30 years ago and has accumulated >1000 neurodegenerative cases. Funds from the University of Pittsburgh Brain Institute have allowed us to broaden and expand our banking efforts. All cases receive a full diagnostic evaluation by a board-certified neuropathologist. Some portions of the brain tissue are banked and are made available to local, national and international investigators for qualified research studies. You may make a request by submitting a “Request for Tissue Specimen” at the website or by contacting us.
Cell Culture and Cytogenetics Facility (CCCF)
The Cell Culture and Cytogenetics Facility provides comprehensive cytogenetics services as well assisting with study design and manuscript preparation.
Services include preparation, laboratory processing and interpretation for:
- Cell culture including primary cell culture of human cells, and EBV transformation of human B-lymphocytes and cell line cryopreservation
- Molecular probes
- Classical and molecular cytogenetic analyses of human and other mammalian cells including Karyotyping
- Cytogenetic harvests
- FISH and molecular genetic procedures requisite for FISH, including polymerase chain reaction (PCR) amplification, fluorescence and light microscopy, darkroom for standard photomicrography and printing as well as digital imaging and printing.
- Cell line authentication
- Mycoplasma testing
These approaches can be used to characterize the karyotype of cells; map the location of new genes, virus, or transgene insertions; monitor established cell lines to rule out interspecies cell culture contamination or other changes during cell culture; ensure the fidelity of embryonic stem cells prior to production of knockout mice; determine the pattern of chromosomal gains and losses; and enumerate copy numbers of chromosomes or cancer-related genes.
Keywords: Animal, Rigor and Reproducibility
Center for Research Computing (CRC)
Contact information for the CRC staff members can be found at https://crc.pitt.edu/people/
The mission of the Center for Research Computing is to increase the impact and productivity of Pitt researchers through the use of advanced computing. We fulfill this mission by
- providing our community access to cutting-edge computer hardware and software for enabling transformative research,
- providing our community training workshops to educate users how to utilize the computing resources effectively,
- providing extended personalized consultation for improving researchers’ computational workflow and code performance through selection of better algorithms, parallelization techniques, improved use of input-output strategies, etc. We can also assist in grant proposals, justifying the requested computational hardware or personnel support.
An overview of CRC resources can be found at https://crc.pitt.edu/documentation/overview-to-crc-resources/
Hardware computing resources include SMP, GPU, MPI_OPA, and MPI_IB clusters and a High Throughput Computing (HTC) cluster designed for Health Sciences Research. Multiple data storage options are available, each consisting of hundreds of terabytes.
Center for Research on Health Care, Data Center
The CRHC Data Center mission is to support University of Pittsburgh faculty members in conducting high-quality clinical and translational research at the University of Pittsburgh. To meet this objective, the CRHC Data Center provides data management, statistical analysis, and graphics services to all University investigators.
The Food and Drug Administration (FDA) developed guidelines (Title 21 CFR Part 11) for electronic records to ensure the integrity and reliability of the electronic data; the CRHC Data Center creates databases that are compliant with these FDA guidelines.
Center for Simulation and Modeling (SAM)
The former Center for Simulation and Modeling (SaM) is now part of the Center for Research Computing (CRC).
For more information please see the CRC entry in this database or go to www.crc.pitt.edu
Clinical and Translational Science Institute(CTSI)
The mission of the Clinical and Translational Science Institute (CTSI) at the University of Pittsburgh is to improve the efficiency with which biomedical advances translate to improvements in the health of the community. CTSI is transforming the process of clinical and translational research through the provision of research and educational resources, thus training and enabling scientists to generate and translate new biomedical knowledge.
- Research Participant Registry
- Regulatory Core
- Clinical and Translational Research Center
- Design Biostatistics and Ethics Core
Clinical Research Informatics Service (CRIS)
The Clinical Research Informatics Service (CRIS) is a service of the Office of Clinical Research, Health Sciences. CRIS provides honest broker services for University of Pittsburgh faculty; an honest broker serves as a disinterested intermediary between the researcher and the individual whose data are being studied. The use of the honest broker ensures that the investigator is not interacting with those individuals nor recording any identifiable information about them.
This service allows clinical researchers to obtain relevant data and analysis tools from UPMC databases. CRIS can also assist with identification of anonymized potential research subjects or records using the Medical Archival Retrieval System (MARS).
Dietrich School Scientific Stockroom
The Dietriech School Scientific Stockroom (DSS) is an award winning combined stockroom that opened May 20, 2015. The catalog includes products from the former Biological Sciences, Chemistry, and Physics stockrooms, as well as the Excise Tax Free Ethanol Program all in one convenient location. It is a University owned and run internal scientific supplier with inventory management support from Unity Lab Services. New suppliers and products are added regularly. You can pick up your order in the Chevron building or Langley Hall or have them deliver to your building next day. To Order from the DSS Use the DSS Punch-out on PantherExpress via my.pitt.edu.
326 Chevron Science Center
7:30 a.m. to 5 p.m. Monday - Friday
412-624-8551 or 412-624-4260
LANGLEY STATON (alternative stockroom pickup location)
120F Langley Hall/Garage
8 a.m. to 4:30 p.m. Monday - Friday